Research
Below is just sample of some research that has been done for several medical conditions. The number of links listed on this page has no relation to the number of studies done for a particular disease.
Clinical research showing positive effect of medical cannabis on seizures:
- 2013 US study showing seizure reduction in children using cannabidiol-enriched cannabis
- 2013 paper from John Wiley & Sons, showing the therapeuticpotential of cannabinoid medicines (epilepsy is discussed on page 5)
- 2010 UK study that says CBD displays antiepileptiform and antiseizure properties
- 1990 US double-blind study with no results published but “some reduction of seizure frequency” from cannabidiol
- 1981 Double-blind study that shows patients receiving cannabidiol showed improvement of their epilepsy
- 1980 US study showing CBD promising treatment for epilepsy
- 1977 Israeli/Brazilian controlled study of patients showing improvement in epileptic symptoms from cannabidiol
Other examples of clinical research showing positive effect of medical cannabis on epilepsy and seizures:
- 2013 UK study indicating CBDV is an anticonvulsant and a potential medicine for epilepsy
- 2012 UK study indicating CBD is safe and has powerful cumulative anticonvulsant effects, superior to other anti-epileptic drugs
- 2012 UK study indicating CBD is an anticonvulsant and a potential medicine for epilepsy
- 2012 Swiss study analyzing 34 different clinical trials and summarizing Cannabidiol’s therapeutic targets
- 2011 UK study analyzing Phytocannabinoids as novel therapeutic agents in Central Nervous System disorders
- 2007 US study and summary showing marijuana could be an effective antieplieptic treatment for partial epilepsy
- 2006 US study showing the anti-epileptic effects of binding to endocannabinoid receptors
- 2005 UK and US study showing combination of THC and CBD increases clinical efficacy while reducing adverse events
- 2005 Italian study showing no severe side effects and improved consciousness in children
- 2003 US National Institute of Health patent 6,630,507 “Cannabinoids as antioxidants and neuroprotectants”
- 2003 UK study showing isolated cannabidiol (similar to Epidiolex) without the other phytochemicals of the whole plant is NOT effective as an anti-convulstant for seizures
- 2003 German study actually showing positive effects of THC in children with severe neurological disorders
- 1978 US study on treating epileptic rats with cannabis
- 1949 US study indicating cannabis controls seizures
Alzheimer’s:
- 2014 US study on the potential therapeutic effects of THC on Alzheimer’s Disease
- 2006 US study finding that marijuana’s active ingredient shown to inhibit primary marker of Alzheimer’s Disease
Cancer:
- 2006 British study showing tetrahydrocannabinol (THC) and other cannabinoids inhibit tumor growth and angiogenesis in animal models, so their potential application as antitumoral drugs has been suggested
- 2012 US study showing that CBD inhibits human breast cancer cell proliferation and invasion through differential modulation of the extracellular signal-regulated kinase (ERK) and reactive oxygen species (ROS) pathways
- 2010 Spanish study showing Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition
- 2007 US (Harvard) study showing Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo
- 2006 Spanish study showingCannabinoids Induce Apoptosis of Pancreatic Tumor Cells via Endoplasmic Reticulum Stress–Related Genes
Multiple Sclerosis:
- 2014 US study showing cannabis can relieve particular symptoms of MS, including spasticity, pain related to spasms, or central pain from MS lesions
- 2012 UK study showing significant improvement by the cannabis extract Cannador of spasticity and pain.
Parkinson’s Disease:
- 2014 US study showing the mean (SD) total score on the motor Unified Parkinson Disease Rating Scale score improved significantly from 33.1 (13.8) at baseline to 23.2 (10.5) after cannabis consumption (t = 5.9; P < 0.001)
- 2013 Australian study showing thatcannabis holds promise as another treatment option for PD. It can apparently alleviate not only the motor symptoms but also the non-motor symptoms, especially PD-related pain and sleep, thereby improving patient quality of life.
ALS:
- 2004 US study showingdelayed disease progression in mice by treatment with a cannabinoid.
- 2010 US study showing that cannabis might significantly slow the progression of ALS, potentially extending life expectancy and substantially reducing the overall burden of the disease
Mitochondrial Disease:
- 2012 German study showing cannabinoids as regulators of mitochondrial activity, as anti-oxidants and as modulators of clearance processes protect neurons on the molecular level
- 2009 UK study showing neurodegenerative diseases linked directly to mitochondrial malfunction, such as Huntington’s disease and Friedreich’s ataxia, may benefit greatly from CBD –based medicines.
Further Research
- http://www.safeaccessnow.org/research
- http://www.cannabis-med.org/studies/study.php
- https://www.ncbi.nlm.nih.gov/pubmed/
- Example keywords are: cannabis, cannabidiol, cannabinoid, tetrahydracannabinol, OR marijuana along with any medical diagnosis you wish to investigate.